David Baker of the Institute for Protein Design. (UW Photo)Researchers at the University of Washington working on both protein design and the understanding of gravity have been awarded the Breakthrough Prize in life sciences and fundamental physics. The so-called “world’s largest science...
Protein design
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An artist’s depiction shows antiviral mini-binders (the bluish spiral shapes) binding to spike proteins (shown in red) on the surface of the SARS-CoV-2 virus. (Illustration by Institute for Protein Design)Imagine being able to ward off COVID-19 just by spritzing a nasal spray into your nostrils....
This stylized schematic shows a Co-LOCKR protein device coming together on the surface of a cell that has the right combination of cell surface markers to be targeted for attack. Check the end of this report for a detailed description of the process. (Institute for Protein Design Illustration)The...
A cryo-EM map of a portion of the novel coronavirus’ protein structure shows several substructures, including a hairpin-shaped protein that hadn’t been identified previously. (Gao et al. / Science / AAAS)Chinese researchers say they’ve mapped out a key protein structure in the coronavirus...
This is one of the high-scoring protein designs that will be turned into an actual protein binder for testing as an coronavirus-blocking agent. (Stomjoh via Foldit / UW Institute for Protein Design)Who would have thought a video game could identify potential treatments for COVID-19? Researchers at...